Commercially available first aid kits available via normal retail routes have traditionally been intended for treatment of minor injuries only. Typical contents include adhesive bandages, regular strength pain medication, gauze and low grade disinfectant.

Specialised first aid kits are available for various locations and activities, which may focus on specific risks or concerns related to the activity. Kits should also be checked regularly and restocked if any items are damaged or are expired out of date.